Zeta Plus™ ZB Series Filter Cartridges are optimized for clarification of pharmaceutical, biological, bioprocess and cosmetic fluids, in addition to, providing protection of downstream sterilizing grade membrane filters. The strong positive charge provides enhanced reduction of negatively charged contaminants compared to a mechanical filtration mechanism alone.
Accentuating the Positive
As we manufacture Zeta Plus™ ZB Series filter media, we use a charged resin system to bind a positive charge to the filter matrix, permanently forming an interconnected filtration structure with positively charged electrokinetic capture sites. The resulting porous depth filter is a complex network of charge-enhanced flow channels capable of removing bacteria, particulate, cellular debris and submicron contaminants like DNA to a level that mechanical screening alone cannot attain. Zeta Plus™ ZB Series Filter Cartridges can protect downstream membranes, thereby extending filter life and reducing overall filtration costs.
Our family of Zeta Plus™ ZB series filter cartridges are composed of advanced cellulose-based depth filtration media, designed to retain contaminants by both mechanical entrapment and electrokinetic adsorption. Zeta Plus filter media is composed of high surface area filter aids embedded in a cellulose fiber matrix. During the manufacturing process, the ZB resin system incorporated into the filter media imparts a strong positive charge to the filter matrix to permanently form an interconnected filtration structure with positively charged electrokinetic capture sites. The resulting porous depth filter is a complex network of charge-enhanced flow channels capable of removing bacteria, particulate, cellular debris and submicron contaminants to a level which mechanical screening alone cannot achieve.
Zeta Plus Construction
Our cartridges are constructed from individual cells of Zeta Plus™ ZB series filter media assembled together with polypropylene ring seals under predetermined compression and unitized by three, 316 stainless steel bands. Each cell is constructed using molded edge seals and separators for high performance. Gasket material options are available.
Zeta Plus Applications
Blood and blood products
Bioprocess Fluids (bacteria and yeast cell lysates, cell separation)
Protection of downstream processes including membrane filters and chromatography columns
Zeta Plus ZB series filter media is available in a broad range of micron ratings to meet clarification applications. Optimum flow rates vary by application, but in general, lower flux rates often result in longer service life, greater throughputs and superior system economics.
Zeta Plus Scalability
We also offer a range of cartridge sizes, making scale-up easy and predictable, from laboratory scale to pilot plant, and from pilot plant to full production. Filter cartridges are available in 8”, 12”, and 16” diameters, with surface areas ranging from 650 cm² to 3.9 m² per cartridge to make scale-up straight forward and predictable.
We support all Zeta Plus™ ZB Series Filter Cartridges with a Regulatory Support File and Certificate of Quality to support your validation and regulatory submissions. The products are also documented in a Drug Master File (DMF) on record with the US Food and Drug Administration (FDA).
With a range of cartridge sizes, quality tested media and support documentation, Zeta Plus™ ZB Series Filter Cartridges are an ideal choice for many pharmaceutical and biological filtration processes.